Haha, I love the humor. The jaw frame really tops it off.
Your lines and style have a really nice illustrative quality, though three things that stick out to me are left guy's face, the center guy's skull, and the center's clothes folds. The left guy's face is much flatter than the other two. The other two have a nice expressiveness to them but this one looks too posed. I'm afraid I can't pinpoint exactly why that is though - perhaps something with the angle of the far eye? Load of help I am, sorry!
Anywho. Next, the center's skull - His face looks great, it just looks like he's missing part of his skull underneath his hat. Ideally it should be a bit wider to match up with where his jaw and ear fall. (That said, his legs are gone so who am I to judge the condition of his head!
Last, the clothes on the center guy. Of course he's a little worse for the wear on account of his...current situation...but the wrinkles look a little chaotic. They don't follow the stretch of the fabric as nicely as on the other two characters. I'd suggest revisiting them to see if you can consolidate them down to fewer but expressive lines.
Overall, really great work! Definitely a successful piece.
Appreciate the great appraisal! A lot of people have commented that Dreyfuss's face looks a little off. I'm not sure what happened there, honestly. I also appreciate the anatomy notes and I'll try my best to deal with clothing wrinkles better in the future. Cheers!~